The twentieth century is discernable by global events including wars and technological changes focused by the mutual desires of powerful countries as the colonial rule was over and world moved away from closed markets which led to a more connected global economy. In order to remove barriers of trade countries worked hard as a result many regions benefited. Conversely, Asia remained slightly quarantined from international trade. The study is focused on the potential of some countries of Central Asia to become significant players in the global trade market due to their rich oil and gas resources such as Uzbekistan and Turkmenistan. Central Asia looks for support to engage in trade, including Pakistan. However, challenges like fear of Russian influence, Islamic concerns, and the dominance of the United States have created confusion in the region. Turkey, Iran, Russia, and Pakistan all have different approaches, which complicates the situation.